Ocular implant with anchor and therapeutic agent

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The Glaukos Corporation patent solves the following problem:

About two percent of people in the United States have glaucoma. Glaucoma is a group of eye diseases that cause pathological changes in the optic disk and visual field loss leading to blindness if left untreated. Intraocular pressure elevation is the major etiologic factors in all glaucomas.

Our analysis of this patent is as follows:

Glaukos Corporation’s patent US 8273050 B2 deals with Ocular implant with anchor and therapeutic agent.
Ocular implants and methods for treating ocular disorder given. One method involves inserting an implant into a front chamber of the eye. implant is a therapeutic drug or agent, and advanced into the front room to a rear location of a cornea of ​​the eye. At least a portion of the implant is placed into the eye tissue in its place. The therapeutic drug implant is exposed to aqueous humor. In a way, an anchor used to retain the implant in the eye tissue.

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Downhole progressive pressurization actuated tool and method of using the same

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The Halliburton Energy Services Inc. patent solves the following problem:

Hydrocarbon-producing wells are often stimulated by hydraulic fracturing operations, where a fracturing fluid can be introduced into a portion of a subterranean formation penetrated by a wellbore to a hydraulic pressure enough to create or enhance at least one fracture. Encouraging or treatment wellbore such by increased hydrocarbon production from the well. Broken equipment can be incorporated in a casing string used throughout the production process. Another casing string comprising fracturing equipment may be removably placed in the wellbore during and / or after surgery. The casing string and broken equipment can run into the wellbore to a predetermined depth. Various zones in underground construction will be isolated by the operation of one or more packers, which may also help to ensure the casing string and broke the equipment in place.

Our analysis of this patent is as follows:

Halliburton Energy Services Inc.’s patent US 8272443 B2 deals with Downhole progressive pressurization actuated tool and method of using the same.
A method of service in a subterranean formation comprising placing a wellbore servicing tool consisting of an axial flowbore in a wellbore, to make a first application of pressure in the axial flowbore wellbore service device; where the pressure in the wellbore service tool is at least a first surface of the door during the first use of pressure, allowing the pressure in the axial flowbore after the first use of the pressure to fall under a first lower gates, make a second application of pressure to the axial flowbore wellbore servicing tool, where the pressure in the wellbore service tool is at least a second upper door during the second application of pressure, allowing a second pass the pressure in the axial flowbore following the second application of pressure to fall a second lower gate, and communicating with a fluid in the wellbore, the underground formation, or both through one or more ports in the wellbore service tool.

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Tubular valve system and method

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The Baker Hughes Incorporated patent solves the following problem:

Some industries, such as downhole drilling and completion industry, for example, the use of tubular system valve to open to a plurality of ports by a tubular along a longitudinal area the tubular. Selectively opening the ports usually involves running a shifting tool within the tubular valve each receptive to the device, including the valve switching device, and shifting the valve to the desired position before withdraw the transfer tool from the tubular. This procedure, although effective, cause downtime in operation during the running, shifting withdrawal and transfer device. Systems and methods that reduce the downtime was well received in the art.

Our analysis of this patent is as follows:

Baker Hughes Incorporated’s patent US 8272445 B2 deals with Tubular valve system and method.
A tubular valve system including a tubular having a plurality of ports therethrough; a plural strokable sleeve disposed in the tubular configured stroke in response to an external input; and a lot of motion detail rendering cast in at least one of the tubular and plural strokable sleeve configured to change a stroke plural strokable sleeve after a selected number the plague of being open in at least one of the plurality of ports and procedures.

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Lipid formulated dsRNA targeting the PCSK9 gene

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The Alnylam Pharmaceuticals, Inc. patent solves the following problem:

Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family. The other eight mammal subtilisin proteases, PCSK1 PCSK8 (also called PC1 / 3, PC2, furin, PC4, PC5 / 6, PACE4, PC7, and S1P / Ski-1) proprotein convertases processing in a wide kind of secretory proteins road and play a role in various biological processes (Bergeron, F. (2000) J. mol. Endocrinol. 24, 1-22, Gensberg, K., (1998) Semin. Cell Dev. Biol. 9, 11-17, Seidah, NG (1999) Brain Res. 848, 45-62, Taylor, NA, (2003) FASEB J. 17, 1215-1227, and Zhou, A., (1999) J. Biol. Chem. 274, 20745- 20748). PCSK9 suggested to play a role in cholesterol metabolism. PCSK9 mRNA expression-regulated dietary cholesterol feeding in rats (Maxwell, KN, (2003) J. Lipid Res. 44, 2109-2119), the regulated statins in HepG2 cells (Dubuc, G., (2004 ) Arterioscler. Thromb. Vasc. Biol. 24, 1454-1459), and to regulate the sterol regulatory element binding protein (SREBP) transgenic mice (Horton, JD, (2003) Proc. Natl. Acad. Sci. USA 100, 12027 -12032), similar to the cholesterol biosynthetic enzymes and low-density lipoprotein receptor (LDLR). Furthermore, PCSK9 missense mutations were associated with a form of autosomal dominant hypercholesterolemia (Hchola3) (Abifadel, M., et al. (2003) Nat. Genet. 34, 154-156, Timms, KM (2004 ) Hum. genet. 114, 349-353, Leren, TP (2004) Clin. genet. 65, 419-422). PCSK9 also play a role in determining levels of LDL cholesterol in the general population, because the single nucleotide polymorphisms (SNPs) associated with the level of cholesterol in a Japanese population (Shioji, K., (2004) J. Hum. Genet. 49, 109-114).

Our analysis of this patent is as follows:

Alnylam Pharmaceuticals, Inc.’s patent US 8273869 B2 deals with Lipid formulated dsRNA targeting the PCSK9 gene.
This invention relates to compositions and methods of use of lipid formulated siRNA targets a PCSK9 gene.

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Stapler for mucosectomy

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The Tyco Healthcare Group Lp patent solves the following problem:

Our analysis of this patent is as follows:

Tyco Healthcare Group Lp’s patent US 8272555 B2 deals with Stapler for mucosectomy.
The head of a stapler for mucosectomy consists of an external cup-shaped body (1) where an internal goblet-shaped body (2) is concentrically and slidingly located, on the edge of a circle edge (3) strong. The internal cup-shaped body (2) provided with a central hole (5) in which a rod (6) is slidingly inserted, the end (7) a pat (8; 8) strong . One or more annular grooves (11), similar to and appropriately spaced from one another, are formed on the lateral surface of the rod (6) perpendicularly to the axis thereof. Said grooves (11) intended to receive a portion of the mucosa (9 a) that includes a purse string suture as mucosa tied around the rod (6). By retracting the rod (6) in the central hole (5) of the stem (2 a) the internal goblet-shaped body (2) of the mucosa, which led to internal goblet-shaped body (2) . Pat (8; 8) and the circular edge (3) moved up one to one, appropriately, to cut the tissue when the stapler in a closed position.

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Surgical device having multiple drivers

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The Tyco Healthcare Group Lp patent solves the following problem:

A variety of surgical device is a linear clamping, cutting and stapling device. Such a device could be used in an operation to resect a cancerous or anomalous tissue from a gastro-intestinal tract. A conventional linear clamping, cutting and stapling instrument shown in FIG. 1. The device includes a pistol grip-styled structure having an elongated shaft and distal portion. The distal portion includes a pair of scissors-styled elements interesting, imposing restrictions on the open ends of the colon closed. In the device, one of the two scissors-styled interesting elements, like the anvil portion, moves or pivots relative to the general framework, while the other gripping element remains fixed relative to the general framework . The actuation of this scissoring device (the turnable part pat) controlled by a holding account to continue in the shaft.

Our analysis of this patent is as follows:

Tyco Healthcare Group Lp’s patent US 8272554 B2 deals with Surgical device having multiple drivers.
A surgical device is given, the surgical device including a first driver to do a first function activities; A second driver to perform a second function activities; a first rotatable drive shaft configured, upon actuation, causing selective engagement with one of the first and second drivers on a second rotatable drive shaft, wherein the second rotatable drive shaft cast , formed to drive selectively participate in one of the first and second drivers. Third and fourth drivers may also be included. The driver can move around in a shaft of the surgical device family, and about the longitudinal axis, with a handle; act in a jaw portion relative of arrows, move a first jaw relative to a second jaw; and / or move to a surgical member within the second jaw.

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Metadata communication system

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The Ricoh Company, Ltd. patent solves the following problem:

Printing devices are devices that print found in physical media, such as paper or transparent sheets. Printing devices include printers and multi-function peripherals (MFPs) such as the Ricoh Aficio 5560 systems. Often, a printing device receives information from a computer through a network or cable. The printing device print text / or pictures that represent the data.

Our analysis of this patent is as follows:

Ricoh Company, Ltd.’s patent US 8271621 B2 deals with Metadata communication system.
Techniques for communicating metadata declared. According to one technique, a device comprising a configuration module. The configuration module contains and refers to a table mapping. For example, each mapping table mapping that shows a pattern, a recovery protocol, and a packaging protocol. Mapping table, a particular acquisition or packaging protocol can map more than one pattern. The device consists of one or more separate procurement implementation protocol modules and packaging protocol modules. The device receives the request of a client. The device selects an acquisition protocol to interpret the request, and translates the request to use that protocol. The device uses the mapping table to determine a packaging protocol that maps the standard client. The device uses the selected packaging protocol package, the proper form, the requested metadata. Dodge gave appropriately packaged metadata back to the client.

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System and method for econometrically-based grant management

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The Shulman Steven M patent solves the following problem:

Aspects disclosed here relates to systems and methods for managing the funding of academic research and especially to systems and methods for managing the portfolio of research grants.

Our analysis of this patent is as follows:

Shulman Steven M’s patent US 8271372 B1 deals with System and method for econometrically-based grant management.
Systems and procedures for grant management given. In one example, a computer system tracks present proposals, aimed at a conversion ratio that determines the percentage of grant proposals that had been converted into project success and the future research fund based on past successes remain active and project proposal number and the ratios of conversion.

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Modification of airways by application of ultrasound energy

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The Asthmatx, Inc. patent solves the following problem:

The invention relates to a method for the treatment of lung diseases, and particularly, the invention relates to a method of increasing the gas exchange in the lungs by hardening an airway into the lungs.

Our analysis of this patent is as follows:

Asthmatx, Inc.’s patent US 8267094 B2 deals with Modification of airways by application of ultrasound energy.
By increasing the gas exchange lung caused by damaging cells in the lungs, damaging tissue, causing trauma, and / or destroy airway smooth muscle tone with a device inserted into a passage the air in the lungs. The damage lung cells, damaging tissue, causing trauma, and the destruction of airway smooth muscle tone with the device can be any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid into the trachea; delivering a gas into the trachea; puncturing the airway; tearing the airway; Cutting the airway; applying ultrasound to the airway; and applying ionizing radiation into the airway.

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DRM scheme extension

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The Telefonaktiebolaget Lm Ericsson (Publ) patent solves the following problem:

In society today there are many situations where it would be useful to be able to reproduce the details of a certain activity or place.

Our analysis of this patent is as follows:

Telefonaktiebolaget Lm Ericsson (Publ)’s patent US 8272063 B2 deals with DRM scheme extension.
One method for achieving a secure recording and saving a recorded activity based on an expected digital Rights Management (DRM) system. A recording and storage method established, in response to the recognition of one or more factors in a device operated by a user equipment. On the basis of one or more triggers a Rights issuer is located, and a Recording and Secrecy Instruction (RSI) is derived from the RI, to use a current standard of DRM. Based on the RSI, a reliable storage for storing the recorded activity is located, and one or more recording method, which includes one or more recording equipment, activated and managed devices. Before the recorded content to send to reliable storage, a protected inner generated from the recorded content, as in the RSI.

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