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The Sanford-Burnham Medical Research Institute patent solves the following problem:
A major obstacle to progress in the treatment of cancer in the relative lack of agents that selectively target cancer while saving on normal tissue. For example, radiation therapy and surgery, and general local treatment, causing substantial damage to normal tissue in the treatment field, resulting in scars and loss of normal tissue. Chemotherapy, compared to the total administered systemically, causing substantial damage to organs such as the bone marrow, mucosae, skin and small intestine, undergo rapid cell turnover and continuous cell division. As a result, undesirable side effects such as nausea, hair loss and drop in blood cell count often occur when a cancer patient being treated with a chemotherapeutic drug. The undesirable side effects that can limit the amount of a drug that can be safely administered, thus hampering survival rate and impacting the quality of patient life.
Our analysis of this patent is as follows:
Sanford-Burnham Medical Research Institute’s patent US 8815804 B2 deals with Methods and compositions related to targeting tumors and wounds.
Disclosed compositions and methods useful for targeting tumors, areas of damage and blood clots. The compositions and methods based on peptide sequences that selectively bind and family of tumors, areas of damage and blood clots in animals. The declared target is useful for delivering therapeutic agents and detect tumors, areas of damage and blood clots.
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