Protect your idea by filing a Provisional or Utility Patent Application with the PowerPatent Patent Service. It’s easy and fully backed by patent lawyers – and you don’t have to pay until you’re done.
The Cbio Limited patent solves the following problem:
A central part of the host defense system against invading bacteria, fungal, yeast and viral pathogens involves the successful recognition of the pathogen, or components thereof, with the cellular receptor to induce a signaling cascade resulting in stimulation of the immune system and the production of various cytokines. A family of receptor that plays a key role in this line of defense is the Toll-like receptor (TLR) family. TLRs expressed in immune cells, including monocytes, macrophages, dendritic cells, B cells and granulocytes, and a variety of other types of cells including the endothelium and epithelium. TLR activation of pathogens, or by molecules derived thereof, accelerate the formulation intracellular signaling primarily the result of activation of transcription factor NF-B (begging, 2002, Trends Immunol 23 :. 509-12) and modulation cytokine production. . However, a series of other paths can also cause, including the P38 mitogen activated kinase, c-Jun N-terminal kinase and extracellular signal-related kinase pathway (Flohe et al, 2003, J Immunol 170: 2340-2348; Triantafilou and Triantafilou, 2002, Trends Immunol 23: 301-304).
Our analysis of this patent is as follows:
Cbio Limited’s patent US 9457062 B2 deals with Chaperonin 10-induced immunomodulation.
The present invention relates to methods for modulating Toll-like receptor signaling in a subject, or at least one cell, tissue or organ thereof, methods for treating or preventing a disease or state in a subject, methods for modulating the production and / or secretion of one or more immunomodulators in a subject, or at least one cell, tissue or organ thereof, wherein said method includes the administration chaperonin 10, and wherein the chaperonin 10 with a Toll-like receptor activation in a cluster. Also thought related compositions and uses thereof.
The revolutionary TRAN&ASSOCIATES provides patent creation and management tools to help inventors protect their inventions using the patent system. Full lawyer support to complete and file the application is available.